English import Amy Jones (60 not out) and skipper Meg Lanning (56) were imperious for the visitors, who sailed past the Heat's 7-146 with 10 balls to spare.
The Scorchers openers put on 129 for the first wicket, all but putting the result beyond doubt before Lanning fell in the 16th over.
"Jonesy took the pressure off me and we were able to build a really big partnership," Lanning said.
"We feel the depth in our batting is a strong point of ours.
"Having myself, Jonesy and Nat Sciver up the top of the order, it's pretty powerful."
Sciver (12 not out) joined player-of-the-match Jones in the middle and finished off proceedings by belting consecutive legside boundaries.
The home side let themselves down by conceding 13 wides after earlier losing 5-26 with the bat.
Lanning won the bat flip and sent the Heat into bat first at Brisbane's Allan Border Field.
Jemma Barsby (2-19), playing against her old side, and Irish quick Kim Garth (2-25) were the Scorchers' best bowlers.
The Scorchers will back up tomorrow morning, taking on the Adelaide Strikers at the same venue from 7:40am AWST.